Police are investigating a fatal crash in Monegeetta on Wednesday night.
It is understood a car crashed into a tree on Kilmore Road, near Melbourne Lancefield Road, about 9.55pm.
Emergency services worked on the female driver, who is yet to be formally identified, but she died at the scene.
Anyone with information can contact Crime Stoppers on 1800 333 000 or www.crimestoppersvic.com.au.